Side effects and complications in the use of drugs: adverse reactions here by medication, it is difficult to separate from the physiological effects associated with nerve blockade (eg, reducing blood pressure, riveted a temporary delay or urinary incontinence) is also difficult to select the state, directly caused by the procedure ( spinal hematoma) or indirectly (meningitis, epidural abscess) due to puncture or conditions associated with loss of fluid tserebrospinalnoyi (postural headache after puncture), hypotension, bradycardia, arrhythmia, cardiac Hearing Level nausea, vomiting, postural headache after puncture, paresthesia, paresis, dysesteziya unintentionally complete spinal block, paraplegia, paralysis, neuropathy, arachnoiditis, muscle weakness, back pain, urinary incontinence or retention, AR, anaphylactic shock, respiratory depression, diplopia. The main pharmaco-therapeutic effects: antiarrhythmic, anesthetic effect, for not only inhibits pain impulses, but impulses of the other modality; rapidly hydrolyzed in weak alkaline medium and tissue after a short latent period is valid for 60-90 min, anesthetic effect of lidocaine at 2-6 times stronger than prokayinu, with local application expands blood vessels, does not riveted local irritating action, with riveted (tissue acidosis) anesthetic activity is reduced, effective Pack-years all types of local anesthesia, dilates vessels, shows no irritating action on the tissue beyond the basic steps of anesthesia, does antiarrhythmic effect; antiarrhythmic activity caused by inhibition of phase 4 (diastolic depolarization) in fibers Purkyn'ye, decrease here inhibition of ectopic foci of excitation, the speed of rapid depolarization (phase 0) has no effect or Negative decreases, increases membrane permeability for potassium ions, accelerates the process of repolarization and shorten potential action, the application of therapeutic doses in the medium does not alter the excitability of sinoatrial node, little effect on conductance and skorotlyvist infarction. expressed fibrotic changes in riveted (for anesthesia by infiltration repens). Method of production of drugs: riveted injection 2%, Weight to 2 sol riveted . Pharmacotherapeutic group: S01VV01 - antiarrhythmic means I B cells. CH, cirrhosis); progression CH (usually as a result of heart block and riveted coagulopathy different genesis, arterial hypotension, psychosis, hysteria. Indications for use drugs: premature ventricular beats and tahiarytmiyi, including Arteriovenous/Atrioventricular G MI in the postoperative period, Mr injection 2% - for local anesthesia in surgery, ophthalmology, otorhinolaryngology, dentistry, aerosol 10% - also for local anesthesia in maxillofacial surgery during endoscopic and other instrumental examinations.
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